Awake Animal PET Imaging with the RatCAP (Rat Conscious Animal PET)

Positron Emission Tomography (PET) is a powerful imaging technique that provides information about functional processes in the body by measuring radiotracer concentration in vivo. Small animal PET imaging is becoming increasingly useful as a tool for biological research, as it allows the investigation of spatio-temporal changes of biological processes with longitudinal, noninvasive measurements on the same animal.

The RatCAP is a novel miniature PET scanner designed to acquire fully 3D images of the rat's brain while directly attached to its head. This allows the animal to be completely mobile, eliminating the confounding effects of anesthesia on image quantitation.

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Research supported by DOE (OBER)